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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ROS1 All Species: 19.39
Human Site: Y807 Identified Species: 42.67
UniProt: P08922 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P08922 NP_002935.2 2347 263915 Y807 Y L Y W T T L Y S V E S T R L
Chimpanzee Pan troglodytes XP_527487 2347 263893 Y807 Y I Y W T T L Y S V E S T R L
Rhesus Macaque Macaca mulatta XP_001110859 2345 263559 Y807 Y L Y W T T L Y S V E S T R L
Dog Lupus familis XP_541215 2048 229894 S597 N Y H I P N I S G A G A L A F
Cat Felis silvestris
Mouse Mus musculus Q78DX7 2340 261949 L816 R L N G E S S L V L Q A Q P W
Rat Rattus norvegicus Q63132 2338 261637 Y802 Y L Y W T T L Y S V E S T R L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518175 2242 244778 A791 R N E T Q I W A I D L E R R V
Chicken Gallus gallus P08941 2311 260942 Y808 Y L Y W A T T Y T V E S A R L
Frog Xenopus laevis O73798 1358 153845
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P13368 2554 287007 S874 V L D V A S Q S A F S I R N I
Honey Bee Apis mellifera XP_394148 2105 237988 V654 Y W S T G H A V E V A R L N G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 96.6 73.4 N.A. 79.8 79.8 N.A. 33.7 53.2 21 N.A. N.A. 23.1 26.8 N.A. N.A.
Protein Similarity: 100 99.5 98.2 79.8 N.A. 88.3 87.9 N.A. 47.7 68.7 34.9 N.A. N.A. 40 45.5 N.A. N.A.
P-Site Identity: 100 93.3 100 0 N.A. 6.6 100 N.A. 6.6 73.3 0 N.A. N.A. 6.6 13.3 N.A. N.A.
P-Site Similarity: 100 100 100 20 N.A. 33.3 100 N.A. 13.3 80 0 N.A. N.A. 26.6 13.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 19 0 10 10 10 10 10 19 10 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 0 0 0 0 0 0 10 0 0 0 0 0 % D
% Glu: 0 0 10 0 10 0 0 0 10 0 46 10 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 10 % F
% Gly: 0 0 0 10 10 0 0 0 10 0 10 0 0 0 10 % G
% His: 0 0 10 0 0 10 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 0 10 0 10 10 0 10 0 0 10 0 0 10 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 55 0 0 0 0 37 10 0 10 10 0 19 0 46 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 10 10 0 0 10 0 0 0 0 0 0 0 19 0 % N
% Pro: 0 0 0 0 10 0 0 0 0 0 0 0 0 10 0 % P
% Gln: 0 0 0 0 10 0 10 0 0 0 10 0 10 0 0 % Q
% Arg: 19 0 0 0 0 0 0 0 0 0 0 10 19 55 0 % R
% Ser: 0 0 10 0 0 19 10 19 37 0 10 46 0 0 0 % S
% Thr: 0 0 0 19 37 46 10 0 10 0 0 0 37 0 0 % T
% Val: 10 0 0 10 0 0 0 10 10 55 0 0 0 0 10 % V
% Trp: 0 10 0 46 0 0 10 0 0 0 0 0 0 0 10 % W
% Tyr: 55 10 46 0 0 0 0 46 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _